Clinical significance of drug cessation on medication-related osteonecrosis of the jaw in patients with osteoporosis.

Journal of the Korean Association of Oral and Maxillofacial Surgeons(2023)

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摘要
A significant increase in bone density throughout follow-up and a lower number of interventions were found in the BP suspension group compared to the non-drug suspension group. Also, BP suspension decreased inflammatory markers in the serum after surgery, resulting in good treatment outcomes. BP suspension is a prognostic factor for MRONJ and should be implemented before surgery.
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关键词
Bisphosphonate-related osteonecrosis of the jaw,Bone density,Drug holiday,Inflammatory marker,Osteoporosis
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