Integrating single-cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour.

Kaiyuan Ji,Lina Chen,Xiaodi Wang,Bolun Wen,Fan Yang,Wenfeng Deng,Yunshan Chen,Guozheng Zhang,Huishu Liu

Clinical and translational medicine（2023）

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摘要

Our analysis comprehensively revealed changes in immune cells, cytokines, and cytokine receptors during labour. It provided a valuable resource to detect and characterize inflammatory changes, yielding insights into the immune mechanisms underlying labour.

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关键词

inflammation,labour,myometrium,single-cell RNA-seq,spatial transcriptomics

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