Influence of Residual Quadrupolar Interaction on Quantitative Sodium Brain Magnetic Resonance Imaging of Patients With Multiple Sclerosis

Investigative Radiology(2023)

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Abstract
Our results showed that residual quadrupolar interactions in white matter regions of the human brain have an influence on aTSC quantification and therefore must be considered, especially in pathologies with expected microstructural changes such as loss of myelin in MS. Furthermore, the more detailed examination of residual quadrupolar interactions may lead to a better understanding of the pathologies themselves.
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Na-23 brain MRI, multiple sclerosis, apparent tissue sodium concentration, 7 T, residual quadrupolar interaction, spin-3/2 simulation
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