Effects of Plasma-Derived Exosomal miRNA-19b-3p on Treg/T Helper 17 Cell Imbalance in Behçet's Uveitis.

Qingyan Jiang,Qingfeng Wang,Shiyao Tan,Jinyu Cai,Xingsheng Ye,Guannan Su,Peizeng Yang

Investigative ophthalmology & visual science（2023）

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摘要

Plasma-derived exosomes from patients with active BU showed a markedly differential miRNA expression in comparison to healthy controls. Highly expressed miRNA-19b-3p could induce a Treg/Th17 cell imbalance, probably by downregulating CD46 expression.

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关键词

Behcet's uveitis, plasma exosomes, miR-19b-3p, CD46, Treg, Th17 cell imbalance

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