Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model.

Ashley S Nemec-Bakk,Vijayalakshmi Sridharan,John W Seawright,Gregory A Nelson,Maohua Cao,Preeti Singh,Amrita K Cheema, Bhaldev Singh,Yaoxiang Li,Igor Koturbash,Isabelle R Miousse,Laura E Ewing,Charles M Skinner,Reid D Landes, John D Lowery,Xiao-Wen Mao,Sharda P Singh,Marjan Boerma

Life sciences in space research（2023）

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摘要

Low dose charged particle irradiation caused mild long-term changes in inflammatory markers, cardiac function, and structure in the rabbit heart, in line with previous studies in mouse and rat models.

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关键词

Cardiovascular system,Degenerative tissue effects,Oxygen ions,Protons,Rabbit model,Space radiation

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