Correlation Between the Increase in Serum Uric Acid and the Rapid Decline in Kidney Function in Adults with Normal Kidney Function: a Retrospective Study in Urumqi, China.
BMC nephrology（2023）
Abstract
To examine the association between elevated serum uric acid (SUA) levels and the rapid decline in kidney function by conducting a retrospective cohort study on a physically healthy population in Urumqi, China. A cohort study of 2,802 physically healthy people with a normal estimated glomerular filtration rate (eGFR) was investigated from 2018 to 2021. The examination procedure included using questionnaires, taking physical measurements, and blood sampling. The rapid decline in kidney function was defined as eGFR > 5 mL·min–1 ·(1.73 m2 )–1 year. The relationship between elevated SUA levels and the rapid decline in kidney function was assessed. When performing the three-year retrospective analysis, 688 (28.55
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Key words
Chronic kidney disease,Kidney function,Serum uric acid,Hyperuricemia,The estimated glomerular filtration rate
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