No laughing matter: Bilateral inner thigh burns secondary to nitrous oxide inhalation

In the UK, nitrous oxide is the second most popular recreational drug used amongst 16–24-year-olds after cannabis. 1 Drug misuse in England and Wales: year ending June 2022. Office for National Statistics. 〈https://www.ons.gov.uk/peoplepopulationandcommunity/crimeandjustice/articles/drugmisuseinenglandandwales/yearendingjune2022〉. Google Scholar Colloquially known as ‘laughing gas,’ nitrous oxide inhalation induces a brief intoxication manifesting with feelings of relaxation and euphoria. During use, the pain threshold is heightened and there is a decreased level of awareness, leaving the user vulnerable to cold contact burns.