Water-soluble terphen[3]arene macrocycle: a versatile reversal agent of neuromuscular blockers.

Yibo Zhao,Longming Chen,Junyi Chen,Jian Li,Qingbin Meng,Andrew C-H Sue,Chunju Li

Chemical communications (Cambridge, England)（2023）

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摘要

Herein we report the design and synthesis of a terphen[]arene derivative functionalised with sulfate acid ester groups. This water-soluble terphen[3]arene host effectively encapsulates a multitude of neuromuscular blocking agents (NMBAs) with high affinity, showing great potential as a NMBAs reversal agent in pharmaceutical research.

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关键词

versatile reversal agent,water-soluble

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