Electrochemical Oxidative Carbon‐atom Multifunctionalization and N‐Cyanation of Imine: Synthesis of (Z)‐N'‐Cyano‐N‐carbamimidothioate

Cyanoimines (C=N-CN) are eliciting increased attention because of their extensive presence in medicine and biologically active molecules. This study demonstrated the use of the electrochemical oxidative carbon-atom multifunctionalization and N-cyanation of imine to synthesize (Z)-N'-cyano-N-carbamimidothioate. This multicomponent reaction showed good step economy, thereby providing a tool to construct various cyanoimines. Moreover, good functional-group tolerance and large-scale synthesis were achieved under metal-free and external-oxidant-free conditions, indicating the potential applicability of this methodology.