RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion.

Kayleah M Meneses, Prita Pandya,Jennifer A Lindemann,Dania S Al-Qasrawi, Ryan A Argo, Celeste M Weems,Danielle J Beetler,Geraldine V Vijay,Irene K Yan,Joy Wolfram,Tushar Patel,Verline Justilien

Cancer research communications（2023）

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摘要

Expression of RAB27B in CSCs leads to elevated levels of EVs that mediate communication between CSCs and BCCs that maintains a stem-like phenotype in NSCLC cells.

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关键词

cancer stem cell phenotype,nsclc cells

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