Combined systemic immune-inflammatory index and prognostic nutritional index predict outcomes in advanced non-small cell lung cancer patients receiving platinum-doublet chemotherapy.

Ruiyun Fan,Ying Chen,Guopeng Xu,Wen Pan,Yantian Lv,Zhongwei Zhang

Frontiers in oncology（2023）

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Abstract

Compared with baseline parameters, the correlation between SII, PNI after 4 cycles of chemotherapy and the chemotherapy effect was more significant. The SII-PNI score after 4 cycles of chemotherapy is an effective prognostic biomarker for advanced NSCLC patients treated with platinum-doublet chemotherapy. Patients with a higher SII-PNI score had a worse prognosis.

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Key words

first-line chemotherapy,non-small cell lung cancer,prognostic nutritional index,survival,systemic immune-inflammation index

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