Pediatric acute erythroid leukemias with monocytic antigen expression and novel chromosomal translocations.

Pediatric blood & cancer(2023)

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Pediatric Blood & CancerEarly View e30333 LETTER TO THE EDITOR Pediatric acute erythroid leukemias with monocytic antigen expression and novel chromosomal translocations Gord Guo Zhu, Gord Guo Zhu Department of Pathology, Cooper University Health Care, Camden, New Jersey, USASearch for more papers by this authorZaina Inam, Zaina Inam Center for Cancer and Blood Disorders, Children's National Hospital, Washington, District of Columbia, USASearch for more papers by this authorAmanda Calleroz, Amanda Calleroz Division of Pathology and Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USASearch for more papers by this authorVinodh Pillai, Vinodh Pillai Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USASearch for more papers by this authorReuven J Schore, Corresponding Author Reuven J Schore [email protected] orcid.org/0000-0002-1582-2168 Center for Cancer and Blood Disorders, Children's National Hospital, Washington, District of Columbia, USA Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA Correspondence Jinjun Cheng, Division of Pathology and Laboratory Medicine Division, Children's National Hospital, Room 1629, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected] Reuven Schore, Center for Cancer and Blood Disorders, Children's National Hospital,, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected]Search for more papers by this authorJinjun Cheng, Corresponding Author Jinjun Cheng [email protected] Division of Pathology and Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USA Departments of Pathology and Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA Correspondence Jinjun Cheng, Division of Pathology and Laboratory Medicine Division, Children's National Hospital, Room 1629, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected] Reuven Schore, Center for Cancer and Blood Disorders, Children's National Hospital,, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected]Search for more papers by this author Gord Guo Zhu, Gord Guo Zhu Department of Pathology, Cooper University Health Care, Camden, New Jersey, USASearch for more papers by this authorZaina Inam, Zaina Inam Center for Cancer and Blood Disorders, Children's National Hospital, Washington, District of Columbia, USASearch for more papers by this authorAmanda Calleroz, Amanda Calleroz Division of Pathology and Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USASearch for more papers by this authorVinodh Pillai, Vinodh Pillai Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USASearch for more papers by this authorReuven J Schore, Corresponding Author Reuven J Schore [email protected] orcid.org/0000-0002-1582-2168 Center for Cancer and Blood Disorders, Children's National Hospital, Washington, District of Columbia, USA Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA Correspondence Jinjun Cheng, Division of Pathology and Laboratory Medicine Division, Children's National Hospital, Room 1629, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected] Reuven Schore, Center for Cancer and Blood Disorders, Children's National Hospital,, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected]Search for more papers by this authorJinjun Cheng, Corresponding Author Jinjun Cheng [email protected] Division of Pathology and Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USA Departments of Pathology and Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA Correspondence Jinjun Cheng, Division of Pathology and Laboratory Medicine Division, Children's National Hospital, Room 1629, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected] Reuven Schore, Center for Cancer and Blood Disorders, Children's National Hospital,, 111 Michigan Avenue NW, Washington, DC, USA. Email: [email protected]Search for more papers by this author First published: 19 April 2023 https://doi.org/10.1002/pbc.30333 Gord Guo Zhu and Zaina Inam contributed equally to this work. Reuven J. Schore and Jinjun Cheng contributed equally to this work. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. REFERENCES 1Chisholm KM, Heerema-McKenney AE, Choi JK, et al. Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children's Oncology Group. Blood Adv. 2020; 4(23): 6000- 6008. doi:10.1182/bloodadvances.2020002712 2Margolskee E, Mikita G, Rea B, et al. A reevaluation of erythroid predominance in acute myeloid leukemia using the updated WHO 2016 Criteria. Mod Pathol. 2018; 31(6): 873- 880. doi:10.1038/s41379-018-0001-2 3Wang SA, Patel KP, Pozdnyakova O, et al. Acute erythroid leukemia with <20% bone marrow blasts is clinically and biologically similar to myelodysplastic syndrome with excess blasts. Mod Pathol. 2016; 29(10): 1221- 1231. doi:10.1038/modpathol.2016.118 4Reichard KK, Tefferi A, Abdelmagid M, et al. Pure (acute) erythroid leukemia: morphology, immunophenotype, cytogenetics, mutations, treatment details, and survival data among 41 Mayo Clinic cases. Blood Cancer J. 2022; 12(11): 147. doi:10.1038/s41408-022-00746-x 5Iacobucci I, Wen J, Meggendorfer M, et al. Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nat Genet. 2019; 51(4): 694- 704. doi:10.1038/s41588-019-0375-1 6Ping N, Sun A, Song Y, et al. Exome sequencing identifies highly recurrent somatic GATA2 and CEBPA mutations in acute erythroid leukemia. Leukemia. 2017; 31(1): 195- 202. doi:10.1038/leu.2016.162 7Takeda J, Yoshida K, Nakagawa MM, et al. Amplified EPOR/JAK2 genes define a unique subtype of acute erythroid leukemia. Blood Cancer Discov. 2022; 3(5): 410- 427. doi:10.1158/2643-3230.BCD-21-0192 8King RL, Siaghani PJ, Wong K, et al. Novel t(1;8)(p31.3;q21.3) NFIA-RUNX1T1 translocation in an infant erythroblastic sarcoma. Am J Clin Pathol. 2021; 156(1): 129- 138. doi:10.1093/ajcp/aqaa216 9Micci F, Thorsen J, Haugom L, Zeller B, Tierens A, Heim S. Translocation t(1;16)(p31;q24) rearranging CBFA2T3 is specific for acute erythroid leukemia. Leukemia. 2011; 25(9): 1510- 1512. doi:10.1038/leu.2011.100 10Kamens JL, Dang J, Shaw TI, et al. Malignant progression of an ancestral bone marrow clone harboring a CIC-NUTM2A fusion in isolated myeloid sarcoma. Mol Cancer Res. 2023: OF1- OF6. doi:10.1158/1541-7786.MCR-22-0544 11Zhang H, Zhan Q, Wang X, et al. TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review. Ann Hematol. 2022; 101(12): 2583- 2600. doi:10.1007/s00277-022-04979-5 12Kanazawa T, Ogawa C, Taketani T, Taki T, Hayashi Y, Morikawa A. TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease. Leuk Lymphoma. 2005; 46(12): 1833- 1835. doi:10.1080/10428190500162203 Early ViewOnline Version of Record before inclusion in an issuee30333 ReferencesRelatedInformation
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CIC::NUT2MA,NFIA::RUNX1T1,NUP98,acute erythroid leukemia
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