Central pontine myelinolysis and locked-IN syndrome associated with tacrolimus after pediatric heart transplantation.

Dimpna C Albert-Brotons, Waleed Alharkan,Reem Beheri, Mohammed AlHaddad, Yasser Alali, Yasser Alheraish, Aziza Chedrawi,Zohair AlHalees

Pediatric transplantation（2023）

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摘要

Physicians should recognize a rapid progression of central pontine myelinolysis and locked-in syndrome in the context of heart transplant and although several factors likely contributed to this outcome, adjustment of immunosuppression including by substituting tacrolimus with sirolimus could be effective.

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central pontine myelinolysis,heart transplant

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