Thiourea derivatives containing 4-arylthiazoles and D-glucose moiety: Design, synthesis, antimicrobial activity evaluation and molecular docking/dynamics simulations

Some substituted glucose-conjugated thioureas 4a-h containing 1,3-thiazole ring were synthesized by reaction of corresponding different subsstituted 2-amino-1,3-thiazoles 2a-h with 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isocyante. Their antibacterial as well as antifungal activity of these...