Recurrent erythema nodosum leprosum leading to secondary renal amyloidosis and nephrotic syndrome in an Indian patient with lepromatous leprosy

International Journal of DermatologyEarly View Correspondence Recurrent erythema nodosum leprosum leading to secondary renal amyloidosis and nephrotic syndrome in an Indian patient with lepromatous leprosy Rhea Ahuja MD, Rhea Ahuja MD Departments of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorShivangi Garg MBBS, Shivangi Garg MBBS Departments of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorAdarsh Barwad MD, Adarsh Barwad MD Department of Pathology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorArunkumar Subbiah DM, Arunkumar Subbiah DM Department of Nephrology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorVishal Gupta MD, Corresponding Author Vishal Gupta MD [email protected] Departments of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this author Rhea Ahuja MD, Rhea Ahuja MD Departments of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorShivangi Garg MBBS, Shivangi Garg MBBS Departments of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorAdarsh Barwad MD, Adarsh Barwad MD Department of Pathology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorArunkumar Subbiah DM, Arunkumar Subbiah DM Department of Nephrology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this authorVishal Gupta MD, Corresponding Author Vishal Gupta MD [email protected] Departments of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, IndiaSearch for more papers by this author First published: 17 April 2023 https://doi.org/10.1111/ijd.16693 Conflict of interest: None. Funding source: None. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. References 1Voorend CG, Post EB. A systematic review on the epidemiological data of erythema nodosum leprosum, a type 2 leprosy reaction. PLoS Negl Trop Dis. 2013; 7:e2440. 2Narang T, Kamat D, Thakur V, Lavania M, Singh I, Ahuja M, et al. Equal rates of drug resistance in leprosy cases with relapse and recurrent/chronic Type 2 reaction: time to revise the guidelines for drug-resistance testing in leprosy? Clin Exp Dermatol. 2022; 47: 297– 302. 3Jindal R, Singh I, Bhardwaj S, Chauhan P. High prevalence of resistance to anti-leprosy of concern. Indian Dermatol Online J. 2022; 13(4): 511– 3. 4Narang T, Bishnoi A, Dogra S, Saikia UN, Kavita X. Alternate anti-leprosy regimen for multidrug therapy refractory leprosy: a retrospective study from a tertiary care center in North India. Am J Trop Med Hyg. 2019; 100(1): 24– 30. 5Sharma S, Sarin RC, Prakash S. Secondary amyloidosis in leprosy. Indian J Dermatol Venereol Leprol. 1978; 44: 31– 3. 6McAdam K. Association of amyloidosis with erythema nodosum leprosum reactions and recurrent neutrophil leucocytosis in leprosy. Lancet. 1975; 2: 572– 6. 7Sanz-Martín N, del Rocío Samillán-Sosa K, De Miguel J, Martínez-Miguel P. Renal amyloidosis in leprosy, an infrequent cause of nephrotic syndrome in Europe. BMJ Case Rep. 2016; 2016:bcr2016216038. 8Mitsuda K, Ogawa M. A study of one hundred fifty autopsies on cases of leprosy. Int J Lepr. 1937; 5: 53– 60. 9Nakayama EE, Ura S, Fleury RN, Soares V. Renal lesions in leprosy: a retrospective study of 199 autopsies. Am J Kidney Dis. 2001; 38: 26– 30. 10Date A, Hariar S, Jeyavarthini SE. Renal lesions and other major findings in necropsies of 133 patients with leprosy. Int J Lepr Other Mycobsct Dis. 1985; 53: 455– 60. 11Silva Junior GB, Daher Ede F, Pires Neto Rda J, Pereira ED, Meneses GC, Araújo SM, et al. Leprosy nephropathy: a review of clinical and histopathological features. Rev Inst Med Trop Sao Paulo. 2015; 57: 15– 20. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation