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Extracellular vesicles secreted from bone metastatic renal cell carcinoma promote angiogenesis and endothelial gap formation in bone marrow in a time-dependent manner in a preclinical mouse model.

Masashi Takeda,Hiromasa Sakamoto,Noboru Shibasaki,Tomohiro Fukui,Toshihiro Magaribuchi,Takayuki Sumiyoshi,Noriaki Utsunomiya,Atsuro Sawada,Takayuki Goto,Takashi Kobayashi,Koji Ueda,Toshinari Yamasaki,Osamu Ogawa,Shusuke Akamatsu

Frontiers in oncology（2023）

Cited 1|Views25
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Abstract
EVs from bone metastatic RCC promote angiogenesis and gap formation in capillary endothelium in bone marrow in a time-dependent manner.
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Key words
angiogenesis,bone metastasis (BM),extracellular vesicle (EV),proteomics,renal cell carcinoma (RCC)
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