Applications of Raman spectroscopy in clinical medicine

FOOD FRONTIERS(2024)

Cited 3|Views32
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Abstract
Raman spectroscopy is a nondestructive and highly effective technique for analyzing biological tissues and diagnosing diseases by providing detailed spectral information about the specific molecular structures of substances. Its efficacy in these applications has been widely recognized, making it a powerful tool in the field. This article presents a comprehensive overview of the latest developments in Raman spectroscopy and its wide-ranging applications in the diagnosis of critical diseases, such as cancer, infections, neurodegenerative diseases, and predicting surgical outcomes. It highlights the significant contributions of Raman spectroscopy in these areas, shedding light on its potential as a valuable diagnostic tool. This article delves into the advancements of Raman spectroscopy in biomedical sciences, with a specific focus on state-of-the-art techniques such as surface-enhanced Raman spectroscopy, resonance Raman spectroscopy, and tip-enhanced Raman spectroscopy. These techniques have shown great potential in various applications within the field. The article explores their use in ex vivo and in vivo medical diagnosis, covering topics such as sample collection, data processing, and the successful establishment of correlations between Raman spectra and biochemical information in specific diseases. Furthermore, the article discusses the limitations of the current research and offers insights into potential future directions for further exploration in the field of Raman spectroscopy in biomedical sciences. Applications of Raman spectroscopy in biomedical sciences. 1. A comprehensive review of latest progress in Raman spectroscopy and its utilization in critical diseases, including cancers, infectious diseases, and neurodegenerative disorders. 2. Discussion of the possibilities of Raman technology serving as a clinical tool for multiple phases of disease management, including screening, guiding surgery, and assessing the effectiveness of treatment. 3. Emphasis on the significance of considering the feasibility of implementing new methods in the identification of biological specimens, and evaluation of multiple factors of the materials used to prepare the samples, including biocompatibility, cost, interference, and repeatability. image
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Key words
biomarkers,COVID-19,disease,optical biopsy,pathological diagnosis,Raman spectroscopy,tissue
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