Brachytherapy is Always on the Tip of My Nose

First, we strongly advocate differentiating cancers of the nasal vestibule from other squamous cell carcinomas (SCC) of the skin. In our opinion, their distinct clinical behavior and serious consequences of surgery on nasal cosmesis and function warrant a tailored approach. 1 Brisson RJ Holtzman AL Who knows when it is right under your nose? A case of cutaneous squamous cell carcinoma with involvement of the nasal vestibule. Int J Radiat Oncol Biol Phys. 2023; 115: 817-818 Abstract Full Text Full Text PDF Scopus (3) Google Scholar Who Knows When it is Right Under Your Nose? A Case of Cutaneous Squamous Cell Carcinoma with Involvement of the Nasal VestibuleInternational Journal of Radiation Oncology, Biology, PhysicsVol. 115Issue 4PreviewA 35-year-old male patient presented with a 1.7-cm skin lesion and raised irregular borders on the nasal columella (Fig. 1A), reporting increasing inflammation and pain at the lesion site over the previous 4 weeks. Testing of shave biopsy tissue demonstrated invasive squamous cell carcinoma with keratoacanthoma features. A 2-stage Mohs surgery (Fig. 1B) resulted in positive peripheral and deep margins along the cartilaginous nasal septum, and incidental perineural invasion of a large caliber nerve >0.1 mm was noted. Full-Text PDF