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Cracking the natriuresis puzzle: Insight from structural biology.

Xiao Yu Tian,Wing Tak Wong,Zhiming Zhu

Med (New York, N.Y.)（2023）

Cited 0|Views27
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Abstract
Sodium chloride cotransporter (NCC) plays a crucial role in regulating blood pressure through Na reabsorption. Recently, in Nature, Fan et al. determined the structure of human NCC and revealed the mechanism of action of thiazide diuretics, establishing the groundwork for future drug development..
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Key words
natriuresis puzzle,structural biology
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