Pharmacokinetics of epinephrine sublingual film following three different administration procedures

David Bernstein,John Oppenheimer,David Golden,Carlos Camargo,Matthew Greenhawt,David Fleischer,Mark Freedman,Gary Slatko,Steve Wargacki

Journal of Allergy and Clinical Immunology（2023）

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摘要

AQST-109 is the first and only sublingual film using a novel prodrug of epinephrine (DESF) being developed for the same target indication as epinephrine injection in the emergency treatment of Type 1 allergic reactions. This study compared the pharmacokinetic parameters of epinephrine following three different administration procedures for DESF.

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pharmacokinetics,epinephrine,sublingual film

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