Impact of short-term discontinuation of ivermectin-based chemoprevention on onchocerciasis transmission in endemic settings with long history of mass drug administration.
PLoS neglected tropical diseases（2023）
Abstract
The continued decline in prevalence and CMFL observed ~2 years after MDA disruption is consistent with mathematical predictions (ONCHOSIM) and shows that additional efforts and resources are not needed to mitigate the effects of short-term MDA disruption in highly endemic settings prior to intervention with long treatment histories.
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Key words
onchocerciasis transmission,chemoprevention,mass drug administration,endemic settings,short-term,ivermectin-based
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