Ultrabright red-emitted aggregation-induced luminescence microspheres-based lateral flow immunoassay for furosemide detection in slimming products

Huihui Chen, Jingyu Wu,Mengjun Zhou, Haoxiang Zhou,Xiangmin Li,Xirui Chen,Hui Zou, Qiao Guo,Yonghua Xiong

Microchemical Journal（2023）

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摘要

•Anti-furosemide mAb with high binding affinity of 2.1 × 109 mol/L was prepared.•An ultrabright red-emitted AIEFMs was used as a signal amplification probe to enhance the detection performance of LFIA.•The proposed AIEFM-LFIA exhibited a high sensitivity to furosemide quantitative determination with a LOD of 0.049 ng/mL.

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关键词

Aggregation-induced luminescent microspheres,Red emission,Lateral flow immunoassay,Furosemide,Slimming products

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