Systematic review and meta-analysis of randomized controlled trials of interventions addressing caregiver distress and burden among cancer caregivers

•Current interventions had no significant effect on reducing caregiver distress.•Five out of 11 studies used a behavioral theory or model.•Interventions included cognitive behavioral therapy, educational programs and supportive care.•Supportive care providers were mostly oncology nurses and family physicians.•Seven out of the 11 studies included supportive care as part of the caregiver intervention.