Polyketides isolated from endophyte Fusarium armeniacum and their cytotoxic activities

Phytochemistry Letters(2023)

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摘要
In addition to the structurally interesting polyketides, four curvicollides E, F, G, and H were isolated and identified via comparison of their spectroscopic data with the literature, along with known curvicollides B and C. All compounds were studied in vitro for their cytotoxic activity against the HeLa cervical cancer human ovarian carcinoma cell lines and 1 showed potent cytotoxic activity (IC50 1.86 μg/mL) among the isolated compounds.
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关键词
Endophyte,Fusarium armeniacum,Digitaria ciliaris,Curvicollides,Cytotoxic
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