Monkeypox virus contamination in an office-based workplace environment, England 2022

medRxiv (Cold Spring Harbor Laboratory)(2022)

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Abstract
In May 2022, an office worker attended their place of work while experiencing prodromal symptoms of monkeypox infection. Environmental sampling performed four days later identified only low levels of monkeypox virus DNA contamination of the worker’s desk, and no contamination elsewhere within the office. Replication-competent virus was not identified. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This work was funded by UKHSA Grant in Aid funding and the NIHR Health Protection Research Unit in Emerging and Zoonotic Infections. The funding source had no involvement in study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the article for publication. JD is supported by the Moh Foundation. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: The investigations performed were a component of the urgent public health investigation performed as part of the UKHSA public health incident response to cases of a high consequence infectious disease in the UK. UKHSA is the national health security agency for England and an executive agency of the UK Government Department of Health and Social Care. The study protocol was subject to internal review by the Research Ethics and Governance Group, which is the UKHSA Research Ethics Committee, and was granted full approval. I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes All data produced in the present work are contained in the manuscript
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Key words
workplace environment,virus,contamination,office-based
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