Effectiveness of mHealth Interventions for Blood Pressure Control among Vulnerable Populations: A Systematic Review

Social determinants of health and sociodemographic differences place some individuals at higher risk for hypertension leading to persisting disparities. While mobile health (mHealth) offers a promising approach to facilitate blood pressure (BP) management, it remains unclear which interventions are most effective for addressing disparities in hypertension control. We reviewed the current literature to examine whether mHealth interventions for BP control are effective in improving BP control in populations vulnerable to disparities in hypertension. We conducted a systematic review using multiple databases from January 1, 2009 through December 31, 2020. For inclusion, participants must have elevated blood pressure and belong to a sociodemographic group with known disparities in hypertension. We also tracked specific characteristics of each intervention. Out of the eight articles that met our eligibility criteria for inclusion, five were published in 2018 to 2020. Only four demonstrated a significant reduction in BP and all those interventions incorporated care teams. Despite some evidence of the effectiveness of mHealth interventions for improving BP control among vulnerable groups, more effective interventions are needed, and the quality of studies is overall low. Further research is needed to find the most effective ways to engage diverse communities with mHealth solutions to improve BP control. ### Competing Interest Statement Mark J. Pletcher, MD, MPH has received research grants from the Patient-Centered Outcomes Research Institute (PCORI). All the other authors declare that there is no conflict of interest regarding the publication of this paper. ### Funding Statement The research reported in this publication was supported by Patient-Centered Outcomes Research Institute (PCORI) [PaCR-2017C2-8153]. The content is solely the responsibility of the authors and does not necessarily represent the official views of BPTrack/PCORI ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes The data used to support the findings of this study are available from the corresponding author upon request.