Identification of Human Papillomavirus genotypes in juvenile laryngeal papillomatosis. Three-year experience in a concentration hospital in Puebla, Mexico

Arturo García-Galicia, Clotilde Margarita Andrade-Bonilla,Verónica Vallejo-Ruiz, Blanca Elena Vallejo-Domínguez,Janeth Ramírez-Mendoza,Álvaro José Montiel-Jarquín, Nancy Rosalía Bertado-Ramírez,Jorge Loría-Castellanos

Revista de la Facultad de Medicina Humana(2023)

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Abstract
uvenile laryngeal papillomatosis (JLP) is a chronic benign disease of viral etiology, with an aggressive clinical course. In Mexico, the genotypes of the Human Papilloma Virus (HPV) that cause the disease have been poorly studied. The aim of this study was to identify HPV genotypes in PLJ patients. A descriptive and retrospective study was carried out, the records of patients with PLJ treated in a hospital in Mexico were reviewed, in the period 2018-2021. HPV was identied in all patients for genomes 6, 11, 16, and 18. nine patients were included, 56% women, mean age 9.5 ± 5.7 years; seven patients registered positivity for HPV-11 and 2 for HPV-6. The average age at diagnosis was 2.35 ± 1.77 years, with an average of 12 ± 11.56 surgical procedures. In conclusion, the most frequent genotypes in patients with PLJ were HPV-6 and HPV-11, with the latter predominating.
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human papillomavirus genotypes
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