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277. Reductions in Cue-Induced Craving are Associated With Reductions in Dorsolateral Prefrontal Cortex Activation in Absence of Heavy Drinking During Cognitive Behavioral Therapy for Alcohol Use Disorder

A Benjamin Srivastava,Juan Sanchez-Peña,Frances Levin,John Mariani,Gaurav Patel,Nasir Naqvi

Biological Psychiatry（2023）

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Abstract
Heavy drinking in patients with alcohol use disorder (AUD) is highly automatic, suggestive of deficits in cognitive control. Cognitive behavioral therapy (CBT) is an evidence-based treatment for AUD that is thought to improve cognitive control. However, the neural mechanisms underlying the effects of CBT on cognitive control in AUD remain unclear.
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Key words
Alcohol Use Disorder, Cognitive Behavior Therapy, Dorsolateral Prefrontal Cortex, Alcohol Craving
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