Type 1-type 2 interferon imbalance in dry eye disease.

Trailokyanath Panigrahi, Sharon D'Souza,Vishnu Suresh Babu,Mor M Dickman,Rudy M M A Nuijts,Swaminathan Sethu,Rohit Shetty

Indian journal of ophthalmology（2023）

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摘要

The presence of an imbalance between type 1 and type 2 IFNs in DED patients suggests newer pathogenic processes in DED, plausible ocular surface infection susceptibility in DED patients, and potential therapeutic targets in the management of DED.

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关键词

Dry eye disease,IFNα,IFNγ,IFNλ,TonEBP,hyperosmotic stress,interferons

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