A twist to splicing regulation in haematopoiesis
Nature Cell Biology（2023）
摘要
DNMT3A is best known for its de novo DNA methyltransferase activity. But a new study shows that the protein also has a role in RNA splicing during activation of embryonic and haematopoietic stem cells. This introduces a new perspective for approaching diseases associated with DNMT3A mutations.
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关键词
Cancer stem cells,Stem cells,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells
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