Hypercoagulability evaluation in congenital red blood cell disorders using thrombin generation assay.

Guillaume Feugray,Maximilien Grall,Cécile Dumesnil,Ygal Benhamou,Valery Brunel,Véronique Le Cam Duchez,Agnès Lahary,Paul Billoir

Thrombosis research（2023）

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摘要

•Red blood cell disorders are associated with hypercoagulability state.•Thrombin generation assay evaluates hypercoagulability.•All red blood cell disorders reported hypercoagulability on peak and velocity.•Splenectomy is associated with hypercoagulability in hereditary spherocytosis.•Co-inherited α-thalassemia with sickle cell trait decreased hypercoagulability.

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