Vancomycin Dosing In High-Intensity Continuous Renal Replacement Therapy: A Retrospective Cohort Study.

Nina Srour,Chelsea Lopez,Luma Succar,Peter Nguyen

CRITICAL CARE MEDICINE（2023）

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摘要

This is the first study to evaluate the influence of variable CRRT intensities on vancomycin AUC/MIC. Our findings suggest that vancomycin doses ≥ 15 mg/kg/day are needed to achieve early therapeutic targets in patients on high-intensity CRRT.

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关键词

continuous renal replacement therapy, CVVHD, drug monitoring, vancomycin

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