Dipyridamole Delivery Systems Based on Biomolecules for Aerosol Therapy

Pharmaceutical Chemistry Journal(2023)

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摘要
Inhalation delivery systems, which find use in aerosol therapy, are currently attracting increased attention. A drug administered for inhalation therapy through the respiratory tract has increased bioavailability. Special attention should be paid to the size and shape of the microparticles, which should be in the range 1 – 3 μm and spherical. Microspheres of composites of dipyridamole with bovine serum albumin and lysozyme were produced using a spray-drying procedure in the present work.
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关键词
spray drying,microparticles,proteins,dipyridamole,dissolution kinetics
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