Thrombotic thrombocytopenic purpura in pediatrics. A Case Report

Thrombotic thrombocytopenic purpura is a rare entity in pediatrics, but with high mortality without adequate and timely treatment. It is characterized by microangiopathic hemolytic anemia associated with neurological, cardiac, abdominal and less frequently renal signs and symptoms; may be accompanied by fever. In children, the diagnosis is based on clinical and laboratory findings. ADAMTS13 activity < 10% supports but does not confirm the diagnosis and, given the severity of the pathology, the result should not delay the start of treatment. A previously healthy 15-year-old patient with neurological signs associated with hemolytic anemia and thrombocytopenia is presented. During her hospitalization, she was diagnosed with acquired thrombotic thrombocytopenic purpura.