Synthesis of dimeric butenolide catalyzed by various inorganic silver catalysts
TRADITIONAL MEDICINE RESEARCH(2023)
Abstract
This article describes a method for synthesizing butyrolactone dimers using various inorganic silver salt catalysts. The method was successfully applied to alkyl 2-(2-bromopropyl)malonate 1, providing the dimeric butyrolactone 2 when catalyzed by different silver salt catalysts. This synthesis method not only simplifies the original synthetic route, but also cleverly combines with natural product analogs, providing a strategy for the development of natural product polymer analogs in the future.
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Key words
Mikania,sesquiterpenes,dimer,toxicology,silver catalysis
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