Hepatocellular Carcinoma: It Is Time to Focus on Prognosis.

Radiology(2023)

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HomeRadiologyVol. 307, No. 3 PreviousNext Reviews and CommentaryEditorialHepatocellular Carcinoma: It Is Time to Focus on PrognosisKathryn J. Fowler , Victoria Chernyak, Maxime Ronot, Valerie Vilgrain, Azusa Kitao, Jeong Min Lee, Utaroh Motosugi, Bin Song, Hanyu Jiang, Claude B. Sirlin, Mustafa R. BashirKathryn J. Fowler , Victoria Chernyak, Maxime Ronot, Valerie Vilgrain, Azusa Kitao, Jeong Min Lee, Utaroh Motosugi, Bin Song, Hanyu Jiang, Claude B. Sirlin, Mustafa R. BashirAuthor AffiliationsFrom the Department of Radiology, University of California San Diego, 6206 Lakewood St, San Diego, CA 92122 (K.J.F., C.B.S.); Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (V.C.); Department of Radiology, Université Paris Cité, Paris, France (M.R., V.V.); Department of Radiology, Hôpital Beaujon, APHP.Nord, Clichy, France (M.R., V.V.); Department of Radiology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan (A.K.); Department of Radiology, Seoul National University College of Medicine, Seoul, Korea (J.M.L.); Department of Radiology, Kofu Kyoritsu Hospital, Kofu, Japan (U.M.); Department of Radiology, West China Hospital, Chengdu, China (B.S., H.J.); and Department of Radiology, Duke University Medical Center, Durham, NC (M.R.B.).Address correspondence to K.J.F. (email: [email protected]).Kathryn J. Fowler Victoria ChernyakMaxime RonotValerie VilgrainAzusa KitaoJeong Min LeeUtaroh MotosugiBin SongHanyu JiangClaude B. SirlinMustafa R. BashirPublished Online:Apr 4 2023https://doi.org/10.1148/radiol.220884MoreSectionsFull textPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In References1. European Association For The Study Of The Liver; European Organization For Research And Treatment Of Cancer. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 2012;56(4):908–943. [Published correction appears in J Hepatol 2012;56(6):1430.] Crossref, Medline, Google Scholar2. Yoon JH, Park JW, Lee JM. Noninvasive Diagnosis of Hepatocellular Carcinoma: Elaboration on Korean Liver Cancer Study Group-National Cancer Center Korea Practice Guidelines Compared with Other Guidelines and Remaining Issues. Korean J Radiol 2016;17(1):7–24. [Published correction appears in Korean J Radiol 2016;17(2):306.] Crossref, Medline, Google Scholar3. Heimbach JK, Kulik LM, Finn RS, et al. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology 2018;67(1):358–380. Crossref, Medline, Google Scholar4. Bolondi L, Burroughs A, Dufour JF, et al. Heterogeneity of patients with intermediate (BCLC B) Hepatocellular Carcinoma: proposal for a subclassification to facilitate treatment decisions. Semin Liver Dis 2012;32(4):348–359. Medline, Google Scholar5. Lauwers GY, Terris B, Balis UJ, et al. Prognostic histologic indicators of curatively resected hepatocellular carcinomas: a multi-institutional analysis of 425 patients with definition of a histologic prognostic index. Am J Surg Pathol 2002;26(1):25–34. Crossref, Medline, Google Scholar6. Torbenson MS. Morphologic Subtypes of Hepatocellular Carcinoma. Gastroenterol Clin North Am 2017;46(2):365–391. Crossref, Medline, Google Scholar7. Vij M, Calderaro J. Pathologic and molecular features of hepatocellular carcinoma: An update. World J Hepatol 2021;13(4):393–410. Crossref, Medline, Google Scholar8. Fowler KJ, Burgoyne A, Fraum TJ, et al. Pathologic, molecular, and prognostic radiologic features of hepatocellular carcinoma. RadioGraphics 2021;41(6):1611–1631. Link, Google Scholar9. Ronot M, Chernyak V, Burgoyne Aet al. Imaging to Predict Prognosis in Hepatocellular Carcinoma: Current and Future Perspectives. Radiology 2023. https://doi.org/10.1148/radiol.221429. Published online April 4, 2023. Link, Google Scholar10. Chernyak V, Tang A, Do RKG, et al. Liver imaging: it is time to adopt standardized terminology. Eur Radiol 2022. https://doi.org/10.1007/s00330-022-08769-5. Published online April 7, 2022. Crossref, Google ScholarArticle HistoryReceived: Apr 25 2022Revision requested: May 13 2022Revision received: July 5 2022Accepted: July 12 2022Published online: Apr 04 2023 FiguresReferencesRelatedDetailsCited ByReliability of LI-RADS for MRI and CT: Is Excellence Achievable?Sarah A. 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