Inflammatory Mechanisms in Heart Failure with Preserved Ejection Fraction
PHYSIOLOGY(2023)
摘要
Heart failure with preserved ejection fraction (HFpEF) is now the most common form of heart failure and a significant public health concern for which limited effective therapies exist. Inflammation triggered by comorbidity burden is a critical element of HFpEF pathophysiology. Here, we discuss evidence for comorbidity-driven systemic and myocardial inflammation and the mechanistic role of inflammation in pathological myocardial remodeling in HFpEF.
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关键词
heart failure,inflammation,meta-inflammation,myocardial remodeling
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