Baicalin can enhance odonto/osteogenic differentiation of inflammatory dental pulp stem cells by inhibiting the NF-κB and β-catenin/Wnt signaling pathways.

Mengyuan Li,Yumeng Wang,Jing Xue,Qingqing Xu,Yuerong Zhang,Jie Liu,Hai Xu,Zhuo Guan, Chengyue Bian,Guangdong Zhang,Yan Yu

Molecular biology reports（2023）

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摘要

Baicalin can promote odonto/osteogenic differentiation of iDPSCs through inhibition of NF-κB and β-catenin/Wnt pathways, thus providing direct evidence that baicalin may be effective in repairing pulp with early irreversible pulpitis.

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关键词

Baicalin,Dental pulp stem cells,Nuclear factor kappa B,Odonto/osteogenic differentiation,β-catenin/Wnt signaling pathway

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