The impact of obesity on lung function measurements and respiratory disease: A Mendelian randomization study.

Jiayan Liu,Hanfei Xu,L Adrienne Cupples, George T O' Connor,Ching-Ti Liu

Annals of human genetics（2023）

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摘要

We found significant evidence that increased BMI is suggested to be causally related to decreased FVC and FEV1, and increased BMI-adjusted WHR could lead to lower FVC value and higher risk of asthma. Higher BMI and BMI-adjusted WHR were suggested to be causally associated with higher FEV1/FVC.

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