Supplementary Figures from EpCAM Inhibition Sensitizes Chemoresistant Leukemia to Immune Surveillance

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Supplementary Figure 1. Immunofluorescence and flow cytometry staining for EpCAM in leukemia and normal samples and leukemia cell lines. Supplementary Figure 2. Microarray analysis of markedly up-regulated genes in EpCAM-high cells relative to EpCAM-low cells. Supplementary Figure 3. EpCAM-high K562 cells are similar to tumor stem cells. Supplementary Figure 4. Analysis of AE7 specificity by flow cytometry and IHC/IF staining. Supplementary Figure 5. Analysis of the anti-tumor effect of EpCAM antibody in vivo (lung cancer, positive control) and in vitro. Supplementary Figure 6. Analysis of macrophage clearance after clodronate liposome injection by IF staining.

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