Prognostic factors for the development of lower respiratory tract infection after influenza virus infection in allogeneic hematopoietic stem cell transplantation recipients: A Kanto Study Group for Cell Therapy multicenter analysis

Kaito Harada,Makoto Onizuka,Takehiko Mori,Hiroaki Shimizu,Sachiko Seo,Nobuyuki Aotsuka,Yusuke Takeda,Noritaka Sekiya,Machiko Kusuda,Shinichiro Fujiwara, Sawako Shiraiwa, Katsuhiro Shono,Naoki Shingai,Heiwa Kanamori, Mamiko Momoki,Satoru Takada, Junichi Mukae, Shinichi Masuda,Kinuko Mitani,Emiko Sakaida

International Journal of Infectious Diseases（2023）

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摘要

•Lower respiratory tract infection (LRTI) is a feared complication of influenza virus infection in allogeneic hematopoietic stem cell transplantation recipients.•The risk factors and demographics of LRTI are discussed in a large cohort.•Early neuraminidase inhibitor therapy reduces the risk of progression to LRTI in these patients.

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Influenza virus, Secondary pneumonia, Hematopoietic stem cell transplantation

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