Supplementary Results, Materials and Methods, Movie Legends, Figures 1 - 7, Tables 1, 3 - 4 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation

PDF file - 6308KB, Supplementary Figure S1. Gal1 expression in Ela-myc:Gal1 tumors. Supplementary Figure S2. Analysis of ADM-related genes in Ela-myc:Gal1 tumors. Supplementary Figure S3. Effects of Gal1 depletion in necrosis and tumoral stroma in Ela-myc mice. Supplementary Figure S4. Effects of Gal1 downregulation in SK-PC-1 cells in vitro. Supplementary Figure S5. Effects of Gal1 downregulation in PDA cells in vivo.Supplementary Figure S6. PANC-1 xenograft tumor characterization. Supplementary Figure S7. Gal1 downregulation affects genes involved in tumor progression, adhesion and migration. Supplementary Table 1. Tumor invasion and intraperitoneal hemorrhage in Ela-myc:Gal1+/+, Ela-myc:Gal1+/� and Ela-myc:Gal1�/� pancreatic tumors. Supplementary Table 3. Biological Process GO Terms with P < .0005 obtained from the differentially expressed genes in PANC-1 cells control or with low Gal1 levels.