Supplementary Figures 1-6 from T-Cell Trafficking Facilitated by High Endothelial Venules Is Required for Tumor Control after Regulatory T-Cell Depletion

PDF file - 234K, S Figure 1 - Levels of Foxp3+ Tregs and T cell activation following various doses of DT treatment. S Figure 2 - Efficient depletion of Foxp3+ Tregs leads to T cell activation and proliferation. S Figure 3 - T cell accumulation in tumors of DT treated mice. S Figure 4 - Reduced tumor growth rate following depletion of Foxp3+ Tregs does not correlate with the extent of T cell activation S Figure 5 - Treg-HEV+ tumors do not contain LTi cells. S Figure 6 - Restriction of TCR repertoire in a tumor of DT treated mouse