Supplemental Figures S1-S5 from SYK Is a Candidate Kinase Target for the Treatment of Advanced Prostate Cancer

Veerander P.S. Ghotra,Shuning He,Geertje van der Horst, Steffen Nijhoff,Hans de Bont, Annemarie Lekkerkerker,Richard Janssen,Guido Jenster,Geert J.L.H. van Leenders,A. Marije M. Hoogland,Esther I. Verhoef, Zuzanna Baranski,Jiangling Xiong,Bob van de Water,Gabri van der Pluijm,B. Ewa Snaar-Jagalska,Erik H.J. Danen

crossref（2023）

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摘要

Supplemental Figures S1-S5 Figure S1. Whole organism automated bioimaging assay differentiates between androgen independent / metastatic and androgen-dependent / non-metastatic prostate cancer cells. Figure S2. SYK depletion attenuates PC3 dissemination in zebrafish xenografts. Figure S3. Reduced protein expression of SYK in PC3shSYK cells. Figure S4. SYK depletion attenuates PC3 3D ECM invasion. Figure S5. SYK depletion attenuates colony formation but does not affect AKT activity or CD44 protein expression.

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