Supplementary Figures S1-S9 from Cytosolic TMEM88 Promotes Invasion and Metastasis in Lung Cancer Cells by Binding DVLS

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Supplementary Figures S1-S9: Supplementary FigureS1: Expression and localization of TMEM88 in epithelial malignancies and non-small cell lung cancer (NSCLC) cell lines Supplementary FigureS2: Effect of TMEM88 on canonical Wnt signaling and expression of its downstream target genes Supplementary FigureS3: Co-localization of and interaction between TMEM88 and DVLS in different cellular compartments Supplementary FigureS4: Effects of TMEM88 on proliferation, migration, and invasion of NSCLC cells with cytosolic TMEM88 Supplementary FigureS5: Effects of TMEM88 on proliferation and invasion of non-small cell lung cancer cells Supplementary FigureS6: Effects of cytosolic TMEM88 on expression of epithelial-mesenchymal transition (EMT) proteins Supplementary FigureS7: Effect of TMEM88 and DVLS co-transfection on expression of Snail and invasion in NSCLC cells Supplementary FigureS8: Effects of co-transfecting TMEM88 and DVLS on proteins involved in Snail stabilization Supplementary FigureS9: Overexpression of TMEM88 did not influence expression of Snail, occludin, or ZO-1 in cells with membrane-bound TMEM88

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