Supplementary Figrue S3 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen

Figure S3. Heatmap and quantifications for subsets of ChIP-seq data. (A) Heatmap visualization of ERα chromatin binding events in shGFP cells, separately analyzing binding sites shared or unique for vehicle, E2 or 4-OHT conditions, as indicated in Figure 4C. All peaks were vertically aligned and centered on the top of the peak, with a window of 5 kb. Number of binding sites for each subgroup are shown. (B) Quantifications of read count at ERα chromatin binding sites for different subgroups of chromatin as shown in A, with a 2.5 kb window. Y-axis shows average tag count. (C) Heatmap visualization of ERα chromatin binding events in shUSP9X cells, separately analyzing binding sites shared or unique for vehicle, E2 or 4-OHT conditions, as indicated in Figure 4C. All peaks were vertically aligned and centered on the top of the peak, with a window of 5 kb. (D) Quantifications of read count at ERα chromatin binding sites for different subgroups of chromatin as shown in C, with a 2.5 kb window. Y-axis shows average tag count.