Supplementary Figure 1 from Estrogen Receptor Alpha Mediates Progestin-Induced Mammary Tumor Growth by Interacting with Progesterone Receptors at the <i>Cyclin D1/MYC</i> Promoters

PDF file - 251K, (A) Left. C4-HD tumors growing with MPA were untreated or FUL-treated for 48 h and processed for immunohistochemical studies with pER� (Ser167 and Ser118) antibodies. Bar: 60�m. Right. Quantification of positive cells / HPF in untreated or FUL-treated C4-HD tumors. (B) Top. H&E images showing tumor morphology and Ki67 staining after treatment as described in (A). Black arrows show mitotic cells in MPA growing tumors. White arrows show apoptotic cells. Bar: 60�m. Right. Quantification of mitotic or apoptotic cells / HPF in untreated or FUL-treated C4-HD tumors. (C) BCL/XL, BAX and AIF expression after treatment as described in (A). Bar: 60�m.