Supplementary Figures 1-5 from An Integrated Genome-Wide Approach to Discover Tumor-Specific Antigens as Potential Immunologic and Clinical Targets in Cancer

PDF file - 504K, 1) The principle and algorithm of HEPA analysis; 2) The parameters of HEPA analysis; 3) The HEPA score and expression profile of the TSA genes identified in this study; 4) Comparing PARSE and ELISA assay using IGF2BP3 antigen, and detecting autoantibody responses in an independent cohort of 149 lung cancer patients and 123 healthy individuals with PARSE assay; 5) The application of HEPA analysis in discovering therapeutically relevant overexpressed antigens