Supplementary Table S3 from Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity

Nobuya Ishii,Naoki Harada,Eric W. Joseph,Kazuhiro Ohara,Takaaki Miura,Hiroshi Sakamoto,Yutaka Matsuda,Yasushi Tomii,Yukako Tachibana-Kondo,Hitoshi Iikura,Toshihiro Aoki,Nobuo Shimma,Mikio Arisawa,Yoshihiro Sowa,Poulikos I. Poulikakos,Neal Rosen,Yuko Aoki,Toshiyuki Sakai

crossref（2023）

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Abstract

Supplementary Table S3 - PDF file 54K, Binding constant between CH5126766 and non-phosphorylated MEK1. Non-phosphorylated His6-MEK1 (WT) was imobilized and affinities between His6-MEK1 and MEK inhibitors were analyzed with SPR

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