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The baseline comorbidity burden affects survival in elderly patients with acute myeloid leukemia receiving hypomethylating agents: Results from a multicentric clinical study.

Giovanni Marconi,Anna Candoni,Roberta Di Nicola,Chiara Sartor,Sarah Parisi,Mariachiara Abbenante,Jacopo Nanni,Gianluca Cristiano,Letizia Zannoni,Davide Lazzarotto,Benedetta Giannini,Carmen Baldazzi,Lorenza Bandini,Emanuela Ottaviani,Nicoletta Testoni,Chiara Di Giovanni Bezzi,Rania Abd-Alatif,Giulia Ciotti,Renato Fanin,Giovanni Martinelli,Stefania Paolini,Paolo Ricci,Michele Cavo,Cristina Papayannidis,Antonio Curti

Cancer medicine（2023）

Cited 0|Views76
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Abstract
The comorbidity burden may contribute to impact prognosis in addition to disease biology. While the therapeutic armamentarium of elderly AML is improving, a comprehensive approach that combines AML biology with tailored interventions to patients' frailty is likely to fully exploit the anti-leukemia potential of novel drugs.
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Key words
acute myeloid leukemia,elderly,fitness,hypomethylating agents,prognosis
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